Simplified Protocol for Carba NP Test for Enhanced Detection of Carbapenemase Producers Directly from Bacterial Cultures.

نویسندگان

  • Fernando Pasteran
  • Nathalie Tijet
  • Roberto G Melano
  • Alejandra Corso
چکیده

We compared carbapenemase detection among 266 Gram-negative bacilli (161 carbapenemase producers) using the Carba NP tests issued by the CLSI (CNPt-CLSI) and a novel protocol (CNPt-direct) designed for carbapenemase detection direct from bacterial cultures (instead of bacterial extracts required by the CLSI tests). The specificities were comparable (100%), but the CNPt-direct was more sensitive (98% versus 84%). The CNPt-direct was easier to perform due to the direct use of colonies and offered a more robust detection of carbapenemase producers.

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عنوان ژورنال:
  • Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia

دوره 33 1  شماره 

صفحات  -

تاریخ انتشار 2015